Welcome to Hasnain's Home Page
Seyed Ehtesham Hasnain, (born April 13, 1954), obtained his Ph.D from JNU (1980) , New Delhi and worked briefly at
the University of Delhi before leaving for a National Cancer Institute Post Doctoral Fellowship at the University of
Alberta, Canada, where he was subsequently awarded the Alberta Heritage Foundation for Medical Research Fellow
Award to work at the Department of Medicine. He then spent a couple of years at the Texas A & M University, USA and
returned to India in 1987 to work as a Staff Scientist at the National Institute of Immunology (NII). Dr. Hasnain, who was
a Visiting Scientist at Oxford was appointed as the first Director of CDFD in February 1999. In December 2005, he was
appointed by His Excellency, the President of India as the Vice-Chancellor of the University of Hyderabad.

An Honorary Professor at the Jawaharlal Nehru
Centre for Advanced Scientific Research, Bangalore,
he has been nominated by the Prime Minister of India
for the Membership of the Scientific Advisory Council
to the Prime Minister (SAC-PM), the highest decision
and policy making body for Science & Technology for
the country. A former member of the Science and Engineering
Research Coouncil (SERC) of the DST, he is the recipient
of several national and international awards which include
Dr Nityanand Endowment Lecture for Biomedical Research,
Shri Om Prakash Bhasin Award, Goyal Award, G D Birla
Award, Shanti Swarup Bhatnagar Prize, Golden Jubilee
Biotechnology Fellowship Award, Ranbaxy Research
Award and several others.

Dr Hasnain is an elected Fellow of all the major Science Academies in the country, namely, Indian National Science
Academy, Indian Academy of Sciences, National Academy of Sciences, India, Andhra Pradesh Akademi of Sciences,
Hyderabad, etc.

Dr Hasnain has recently became Elected Fellow of the German Academy of Sciences - Leopoldina  (Deutsche
Akademie der Naturforscher Leopoldina) , a 350 year old learned body in Germany.  He is the first Indian to get this
honor.  He was one of the youngest to be elected to the Fellowship of the prestigious Third World Academy of Sciences
(TWAS), a Foreign Academy based in Trieste, Italy.

Dr Hasnain has been associated with the Editorial Board of several peer reviewed journals in India and abroad. He has
also been associated with the Board of Governors/Scientific Advisory Committee/Academic Council of several National
Institutes. Some of these are Jamia Millia Islamia (JMI), Indian Institute of Technology (IIT)  Bombay, Bose Insitute,
Calcutta, L V Prasad Eye Institute, Hyderabad, Tata Memorial Centre (TMC) and Cancer Research Institute (CRI),
Mumbai, Jamia Hamdard, New Delhi, Centre for Cellular and Molecular Biology (CCMB), Hyderabad, Sir Dorabji Tata
Centre for Tropical Diseases, Bangalore, Centre for Molecular Medicine, JNU, New Delhi, Central JALMA Research
Institute of Leprosy, Agra, Indian Institute of Chemical Biology (IICB), Kolkata, Central Drug Research Institute (CDRI),
Lucknow, Centre for Human Genetics, IISc, Bangalore, Institute of Liver and Biliary Sciences, Delhi, Indian
Immunologicals Limited (IIL), Hyderabad.

Dr Hasnain is the Chairman of the Biotechnology Advisory Committee (Government of Andhra Pradesh) and Adviser to
the Chief Minister of Andhra Pradesh on Biotech related issues. He is also the Member of Biotechnology Advisory
Committees of Government of Jharkhand, Government of Gujarat and Government of Kerala.  

Dr Hasnain is a very ardent supporter of Indo-German Science partnership and has been the founder of the idea of
anIndo-German Liaison Office  (IGLO) that facilitates collaborative ties between Indian and German scientists working
in the area of infectious diseases.

The research interests of his laboratory include understanding the mechanism of baculovirus very late gene
transcription and apoptosis, and more recently the functional biology, molecular epidemiology and evolutionary
genetics of Mycobacterium tuberculosis.

Dr. Hasnain has authored more than 175 original research papers and several book chapters. He has about a dozen
patents filed in India and abroad. Dr Hasnain is one of the founder members and Patron of  ISOGEM, a scientific
society headquartered at Sassari in Italy. Dr Hasnain is the co-ordinator of the Mycobacterium w  (Mycobacterium
indicus sp. Nov.) genome sequencing program, India's first whole genome sequencing project.   He is an Associate
Editor and member of Infection Genetics and Evolution, an international journal published by the Elsevier Science.
This website is sponsored and owned by ISOGEM. All content for fair use unless otherwise stated
Last updated  August 28, 2008   
All web related queries to niyaz[at]cdfd.org.in

Scholarly pursuits and Distinctions of Prof.  Hasnain
 Prof Seyed E Hasnain
FNA, FASc, FNASc, FTWAS

Vice-Chancellor
University of Hyderabad
Hyderabad, India
Receiving the Padma Award from H. E.  Dr APJ
Abdul Kalam, the then President of India
In the News

Prestigious International Award to Prof. Seyed E. Hasnain

The Alexander von Humboldt Foundation, Germany has selected
Professor Seyed Ehtesham Hasnain, Vice-Chancellor, University of
Hyderabad, for the highly prestigious Humboldt Research Award
2008. This Award is given to  eminent non-German researchers
whose fundamental discoveries, insights or new theories have had a
lasting impact on their field of specialization and who are expected
to produce cutting edge results . The Humboldt Research Prize
honours the academic achievements to date of internationally
recognized scientists and is valued at  60000 Euros (~ Rs.37 lakhs).  
A not insignificant number of Award Winners has subsequently been
granted a Nobel Prize  says the release from the Humboldt
Foundation.
...Sample publications

1. Ahmed N, Dobrindt U, Hacker J and Hasnain SE
(2008) . Genomic fluidity and pathogenic bacteria:
applications in diagnostics, epidemiology and
intervention. Nature Rev Microbiol. 6: 387-394.

2. Farhana A, Ghosh P, Kumar S, Tyagi AK,
Ehtesham NZ and Hasnain SE (2008). Trafficking of
iron from host to pathogen involves an interplay
between Mycobacterium tuberculosis exporter
protein Rv1348 and importer proteins Rv1349 and
Rv2895c. PLoS ONE (In press).

3. Ahmed N, Saini V...Hasnain SE (2007). Molecular
analysis of a leprosy immunotherapeutic bacillus
provides insights into mycobacterium evolution.
PLoS ONE. 2:e968.

4. Banerjee S, Nandyala AK, Raviprasad P, Ahmed N
and Hasnain SE (2007). Iron dependent Iron binding
activity of M. tuberculosis aconitase. J Bacteriol.
189:4046-52.

5. Gutierrez MC, Ahmed N (joint first authors),
Willery E, Narayanan S, Hasnain SE, Chauhan DS,
Katoch VM, Vincent V, Locht C and Supply P (2006)
Predominance of ancestral lineages of
Mycobacterium tuberculosis in India suggests an
ancient focus of tuberculosis in South Asia.
Emerging Infectious Dis 12: 367-74.  [Media
spotlight -->> click here]

6.  Khan N, Rahim SS, .. Hasnain SE, Mukhopadhyay
S (2006) Hydrogen peroxide inhibits IL-12 p40
induction in macrophages by inhibiting c-rel
translocation to the nucleus through activation of
calmodulin protein. Blood 107:1513-20

7.  Prakash P, Aruna B, Sardesai AA, Hasnain SE
(2005). Purified recombinant hypothetical protein
coded by open reading frame Rv1885c of
Mycobacterium tuberculosis exhibits a
monofunctional AroQ class of periplasmic chorismate
mutase activity. J Biol Chem. 280:19641-48.

8. Banerjee S, Nandyala A, Podili R, Katoch VM,
Murthy KJ, Hasnain SE (2004). Mycobacterium
tuberculosis (Mtb) isocitrate dehydrogenases show
strong B cell response and distinguish vaccinated
controls from TB patients.
Proc Natl Acad Sci U S A. 101:12652-57.

9.  Hasnain SE and Ahmed N (2004) Leptospirosis.
Lancet Infect Dis 4:543-544.

10.  Majeed A A, Ahmed N,.. Gilman R H and Hasnain
S E. (2004) AmpliBASE MT: A Mycobacterium
tuberculosis diversity knowledgebase.
Bioinformatics 20: 989-992.

11.  Ahmed N, Alam M, .. Sechi LA, Gilman RH,
Hasnain SE (2004). Molecular genotyping of a large,
multicentric collection of tubercle bacilli indicates
geographical partitioning of strain variation and has
implications for global epidemiology of
Mycobacterium tuberculosis.  J Clin Microbiol.
42:3240-47.

12.  Choudhary RK, Mukhopadhyay S, Chakhaiyar
P, Sharma N, Murthy KJ, Katoch VM, Hasnain SE
(2004). PPE antigen Rv2430c of Mycobacterium
tuberculosis induces a strong B-cell response. Infect
Immun. 71:6338-43.

13. Kazim SN, Wakil SM, Khan LA, Hasnain SE, Sarin
SK (2002). Vertical transmission of hepatitis B virus
despite maternal lamivudine therapy. Lancet
359:1488-89.

14. Sah NK, Taneja TK, Pathak N, Begum R, Athar M,
Hasnain SE (1999).  The baculovirus antiapoptotic
p35 gene also functions via an oxidant-dependent
pathway. Proc Natl Acad Sci U S A. 96:4838-43.

15.  Shi YP, Hasnain SE, Sacci JB, Holloway BP,
Fujioka H, Kumar N, Wohlhueter R, Hoffman SL,
Collins WE, Lal AA (1999). Immunogenicity and in
vitro protective efficacy of a recombinant multistage
Plasmodium falciparum candidate vaccine. Proc Natl
Acad Sci U S A. 96:1615-20.

For complete list of publications click here
Contact: .vc@uohyd.ernet.in