Viral taxonomy derived from evolutionary genome relationships.

Viral taxonomy derived from evolutionary genome relationships.

We describe a brand new genome alignment-based mannequin for understanding the range of viruses based mostly on evolutionary genetic relationships. This strategy makes use of data principle and a bodily mannequin to find out the knowledge shared by the genes in two genomes.

Pairwise comparisons of genes from the viruses are created from alignments utilizing NCBI BLAST, and their match scores are mixed to supply a metric between genomes, which is in flip used to find out a worldwide classification utilizing the 5,817 viruses on RefSeq. In circumstances the place there isn’t a measurable alignment between any genes, the tactic falls again to a coarser measure of genome relationship: the mutual data of 4-mer frequency.

This ends in a principled mannequin which relies upon solely on the genome sequence, which captures many attention-grabbing relationships between viral households, and which creates clusters which correlate effectively with each the Baltimore and ICTV classifications. The incremental computational price of classifying a novel virus is low and due to this fact newly found viruses might be rapidly recognized and categorised.

The mannequin goes past alignment-free classifications by producing a full phylogeny much like these constructed by virologists utilizing qualitative options, whereas relying solely on goal genes.

These outcomes bolster the case for mathematical fashions in microbiology which may characterize organisms utilizing solely their genetic materials and supply an unbiased verify for phylogenies constructed by people, significantly quicker and extra cheaply than much less trendy approaches.

Viral taxonomy derived from evolutionary genome relationships.
Viral taxonomy derived from evolutionary genome relationships.

Malaria Molecular Epidemiology: An Evolutionary Genetics Perspective.

Malaria is a vector-borne illness that entails a number of parasite species in quite a lot of ecological settings. However, the parasite species inflicting the illness, the prevalence of subclinical infections, the emergence of drug resistance, the scale-up of interventions, and the ecological components affecting malaria transmission, amongst others, are points that change throughout areas the place malaria is endemic.

NPL Antibody

42953-100ul 100ul
EUR 302.4

NPL antibody

70R-18938 50 ul
EUR 522
Description: Rabbit polyclonal NPL antibody

NPL Antibody

1-CSB-PA874830LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NPL. Recognizes NPL from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF; Recommended dilution: WB:1:2000-1:10000, IF:1:50-1:200

NPL Antibody

1-CSB-PA015994GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against NPL. Recognizes NPL from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF

NPL Rabbit pAb

A9210-100ul 100 ul
EUR 369.6

NPL Rabbit pAb

A9210-200ul 200 ul
EUR 550.8

NPL Rabbit pAb

A9210-20ul 20 ul
EUR 219.6

NPL Rabbit pAb

A9210-50ul 50 ul
EUR 267.6

anti- NPL antibody

FNab05820 100µg
EUR 606.3
Description: Antibody raised against NPL

Human NPL Antibody

32962-05111 150 ug
EUR 313.2

NPL cloning plasmid

CSB-CL874830HU1-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the NPL gene.

NPL cloning plasmid

CSB-CL874830HU2-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the NPL gene.

NPL cloning plasmid

CSB-CL874830HU3-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the NPL gene.

NPL Conjugated Antibody

C42953 100ul
EUR 476.4

NPL protein (His tag)

80R-1785 100 ug
EUR 366
Description: Purified recombinant Human NPL protein

NPL ELISA KIT|Human

EF001304 96 Tests
EUR 826.8

Rat NPL shRNA Plasmid

20-abx989297
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human NPL shRNA Plasmid

20-abx962939
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse NPL shRNA Plasmid

20-abx978080
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

NPL Antibody, HRP conjugated

1-CSB-PA874830LB01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NPL. Recognizes NPL from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

NPL Recombinant Protein (Rat)

RP214349 100 ug Ask for price

NPL Antibody, FITC conjugated

1-CSB-PA874830LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NPL. Recognizes NPL from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

NPL Recombinant Protein (Human)

RP021538 100 ug Ask for price

NPL Recombinant Protein (Mouse)

RP154721 100 ug Ask for price

NPL Recombinant Protein (Human)

RP041722 100 ug Ask for price

NPL Recombinant Protein (Human)

RP041725 100 ug Ask for price

NPL Antibody, Biotin conjugated

1-CSB-PA874830LD01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against NPL. Recognizes NPL from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Npl ORF Vector (Rat) (pORF)

ORF071451 1.0 ug DNA
EUR 607.2

NPL ORF Vector (Human) (pORF)

ORF007180 1.0 ug DNA
EUR 114

NPL ORF Vector (Human) (pORF)

ORF013908 1.0 ug DNA
EUR 424.8

NPL ORF Vector (Human) (pORF)

ORF013909 1.0 ug DNA
EUR 424.8

Npl ORF Vector (Mouse) (pORF)

ORF051575 1.0 ug DNA
EUR 607.2

Human NPL Antibody (Biotin Conjugate)

32962-05121 150 ug
EUR 442.8

N-Acetylneuraminate Lyase (NPL) Antibody

20-abx317934
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

N-Acetylneuraminate Lyase (NPL) Antibody

abx235820-100ug 100 ug
EUR 577.2

N-Acetylneuraminate Lyase (NPL) Antibody

abx122123-100ug 100 ug
EUR 469.2

Narcissus pseudonarcissus lectin (NPA/NPL

05-0119-10 10 mg
EUR 277.2

Narcissus pseudonarcissus lectin (NPA/NPL

05-0119-1000 1 g Ask for price

Narcissus pseudonarcissus lectin (NPA/NPL

05-0119-50 50 mg
EUR 866.4

N-Acetylneuraminate Lyase (NPL) Antibody

20-abx113976
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

N-Acetylneuraminate Lyase (NPL) Antibody

abx030633-400ul 400 ul
EUR 627.6

N-Acetylneuraminate Lyase (NPL) Antibody

abx030633-80l 80 µl
EUR 343.2

N-Acetylneuraminate Lyase (NPL) Antibody

20-abx124803
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Npl sgRNA CRISPR Lentivector set (Rat)

K6323701 3 x 1.0 ug
EUR 406.8

Npl sgRNA CRISPR Lentivector set (Mouse)

K4700701 3 x 1.0 ug
EUR 406.8

NPL sgRNA CRISPR Lentivector set (Human)

K1446501 3 x 1.0 ug
EUR 406.8

Human NPL AssayLite Antibody (RPE Conjugate)

32962-05151 150 ug
EUR 513.6

Human NPL AssayLite Antibody (APC Conjugate)

32962-05161 150 ug
EUR 513.6

Human NPL AssayLite Antibody (FITC Conjugate)

32962-05141 150 ug
EUR 513.6

N-Acetylneuraminate Lyase (NPL) Antibody (HRP)

20-abx316724
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human NPL AssayLite Antibody (PerCP Conjugate)

32962-05171 150 ug
EUR 565.2

Npl 3'UTR GFP Stable Cell Line

TU164255 1.0 ml Ask for price

NPL 3'UTR GFP Stable Cell Line

TU065880 1.0 ml
EUR 1672.8

Npl 3'UTR GFP Stable Cell Line

TU264128 1.0 ml Ask for price

N-Acetylneuraminate Lyase (NPL) Antibody (FITC)

20-abx316725
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

N-Acetylneuraminate Lyase (NPL) Antibody (Biotin)

20-abx316726
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

NPL Protein Vector (Rat) (pPM-C-HA)

PV285804 500 ng
EUR 723.6

NPL Protein Vector (Rat) (pPB-C-His)

PV285802 500 ng
EUR 723.6

NPL Protein Vector (Rat) (pPB-N-His)

PV285803 500 ng
EUR 723.6

NPL Protein Vector (Rat) (pPM-C-His)

PV285805 500 ng
EUR 723.6

NPL Protein Vector (Human) (pPM-C-HA)

PV028719 500 ng
EUR 394.8

NPL Protein Vector (Human) (pPM-C-HA)

PV055631 500 ng
EUR 577.2

NPL Protein Vector (Human) (pPM-C-HA)

PV055635 500 ng
EUR 577.2

NPL Protein Vector (Mouse) (pPM-C-HA)

PV206300 500 ng
EUR 723.6

NPL Protein Vector (Human) (pPB-C-His)

PV028717 500 ng
EUR 394.8

NPL Protein Vector (Human) (pPB-N-His)

PV028718 500 ng
EUR 394.8

NPL Protein Vector (Human) (pPM-C-His)

PV028720 500 ng
EUR 394.8

NPL Protein Vector (Human) (pPB-C-His)

PV055629 500 ng
EUR 577.2

NPL Protein Vector (Human) (pPB-N-His)

PV055630 500 ng
EUR 577.2

NPL Protein Vector (Human) (pPM-C-His)

PV055632 500 ng
EUR 577.2

NPL Protein Vector (Human) (pPB-C-His)

PV055633 500 ng
EUR 577.2

NPL Protein Vector (Human) (pPB-N-His)

PV055634 500 ng
EUR 577.2

NPL Protein Vector (Human) (pPM-C-His)

PV055636 500 ng
EUR 577.2

NPL Protein Vector (Mouse) (pPB-C-His)

PV206298 500 ng
EUR 723.6

NPL Protein Vector (Mouse) (pPB-N-His)

PV206299 500 ng
EUR 723.6

NPL Protein Vector (Mouse) (pPM-C-His)

PV206301 500 ng
EUR 723.6

Npl 3'UTR Luciferase Stable Cell Line

TU114255 1.0 ml Ask for price

NPL 3'UTR Luciferase Stable Cell Line

TU015880 1.0 ml
EUR 1672.8

Npl 3'UTR Luciferase Stable Cell Line

TU214128 1.0 ml Ask for price

Npl sgRNA CRISPR Lentivector (Rat) (Target 1)

K6323702 1.0 ug DNA
EUR 184.8

Npl sgRNA CRISPR Lentivector (Rat) (Target 2)

K6323703 1.0 ug DNA
EUR 184.8

Npl sgRNA CRISPR Lentivector (Rat) (Target 3)

K6323704 1.0 ug DNA
EUR 184.8

Rat N acetylneuraminate lyase(NPL) ELISA kit

E02N0555-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat N acetylneuraminate lyase(NPL) ELISA kit

E02N0555-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat N acetylneuraminate lyase(NPL) ELISA kit

E02N0555-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig N acetylneuraminate lyase(NPL) ELISA kit

E07N0555-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig N acetylneuraminate lyase(NPL) ELISA kit

E07N0555-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig N acetylneuraminate lyase(NPL) ELISA kit

E07N0555-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog N acetylneuraminate lyase(NPL) ELISA kit

E08N0555-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog N acetylneuraminate lyase(NPL) ELISA kit

E08N0555-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog N acetylneuraminate lyase(NPL) ELISA kit

E08N0555-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Npl sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4700702 1.0 ug DNA
EUR 184.8

Npl sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4700703 1.0 ug DNA
EUR 184.8

Npl sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4700704 1.0 ug DNA
EUR 184.8

NPL sgRNA CRISPR Lentivector (Human) (Target 1)

K1446502 1.0 ug DNA
EUR 184.8

NPL sgRNA CRISPR Lentivector (Human) (Target 2)

K1446503 1.0 ug DNA
EUR 184.8

NPL sgRNA CRISPR Lentivector (Human) (Target 3)

K1446504 1.0 ug DNA
EUR 184.8

Recombinant Human NPL Protein, His, E.coli-1mg

QP12870-1mg 1mg
EUR 3308.4

Recombinant Human NPL Protein, His, E.coli-5ug

QP12870-5ug 5ug
EUR 186

Rat N-acetylneuraminate lyase (NPL) ELISA Kit

abx391656-96tests 96 tests
EUR 1093.2

Goat N acetylneuraminate lyase(NPL) ELISA kit

E06N0555-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat N acetylneuraminate lyase(NPL) ELISA kit

E06N0555-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat N acetylneuraminate lyase(NPL) ELISA kit

E06N0555-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Recombinant Human NPL Protein, His, E.coli-20ug

QP12870-20ug 20ug
EUR 241.2

Mouse N acetylneuraminate lyase(NPL) ELISA kit

E03N0555-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse N acetylneuraminate lyase(NPL) ELISA kit

E03N0555-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse N acetylneuraminate lyase(NPL) ELISA kit

E03N0555-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human N acetylneuraminate lyase(NPL) ELISA kit

E01N0555-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human N acetylneuraminate lyase(NPL) ELISA kit

E01N0555-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human N acetylneuraminate lyase(NPL) ELISA kit

E01N0555-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse N- acetylneuraminate lyase, Npl ELISA KIT

ELI-36925m 96 Tests
EUR 1038

Human N- acetylneuraminate lyase, NPL ELISA KIT

ELI-21267h 96 Tests
EUR 988.8

pBluescriptR-NPL

PVT18192 2 ug
EUR 277.2

Mouse N-acetylneuraminate lyase (NPL) ELISA Kit

abx389975-96tests 96 tests
EUR 1093.2

Human N-acetylneuraminate lyase (NPL) ELISA Kit

abx381863-96tests 96 tests
EUR 1093.2

Rabbit N acetylneuraminate lyase(NPL) ELISA kit

E04N0555-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit N acetylneuraminate lyase(NPL) ELISA kit

E04N0555-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit N acetylneuraminate lyase(NPL) ELISA kit

E04N0555-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey N acetylneuraminate lyase(NPL) ELISA kit

E09N0555-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey N acetylneuraminate lyase(NPL) ELISA kit

E09N0555-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey N acetylneuraminate lyase(NPL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Such complexities have propelled the examine of parasite genetic range patterns within the context of epidemiologic investigations. Importantly, molecular research point out that the time and spatial distribution of malaria circumstances replicate epidemiologic processes that can not be absolutely understood with out characterizing the evolutionary forces shaping parasite inhabitants genetic patterns. Although broad in scope, this evaluation within the Microbiology Spectrum Curated Collection: Advances in Molecular Epidemiology highlights the necessity for understanding inhabitants genetic ideas when decoding parasite molecular knowledge.

First, we focus on malaria complexity when it comes to the parasite species concerned. Second, we describe how molecular knowledge are altering our understanding of malaria incidence and infectiousness. Third, we examine completely different approaches to generate parasite genetic data within the context of epidemiologically related questions associated to malaria management. Finally, we describe a couple of Plasmodium genomic research as proof of how these approaches will present new insights into the malaria illness dynamics. *This article is a part of a curated assortment.

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