Mouse CRBN(Cereblon) ELISA Kit
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Human Cereblon (CRBN) ELISA Kit |
DLR-CRBN-Hu-48T |
DL Develop |
48T |
EUR 620.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Cereblon (CRBN) in samples from tissue homogenates, cell lysates or other biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
DLR-CRBN-Hu-96T |
DL Develop |
96T |
EUR 807.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Cereblon (CRBN) in samples from tissue homogenates, cell lysates or other biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
RD-CRBN-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 625.2 |
Human Cereblon (CRBN) ELISA Kit |
RD-CRBN-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 867.6 |
Human Cereblon (CRBN) ELISA Kit |
RDR-CRBN-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 652.8 |
Human Cereblon (CRBN) ELISA Kit |
RDR-CRBN-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 907.2 |
Mouse Cereblon (CRBN) ELISA Kit |
20-abx153810 |
Abbexa |
-
EUR 8853.60
-
EUR 4719.60
-
EUR 1093.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Mouse Cereblon (CRBN) ELISA Kit |
SEG676Mu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5834.88 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cereblon (CRBN) in Tissue homogenates and other biological fluids. |
Mouse Cereblon (CRBN) ELISA Kit |
SEG676Mu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 585.7 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cereblon (CRBN) in Tissue homogenates and other biological fluids. |
Mouse Cereblon (CRBN) ELISA Kit |
SEG676Mu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 785.28 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cereblon (CRBN) in Tissue homogenates and other biological fluids. |
Mouse Cereblon (CRBN) ELISA Kit |
SEG676Mu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3173.76 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cereblon (CRBN) in Tissue homogenates and other biological fluids. |
Mouse Cereblon (CRBN) ELISA Kit |
4-SEG676Mu |
Cloud-Clone |
-
EUR 5895.60
-
EUR 3114.00
-
EUR 786.00
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Cereblon (CRBN) in samples from Tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species. |
ELISA kit for Mouse CRBN (Cereblon) |
ELK7246 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Cereblon from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Mouse Cereblon (CRBN) CLIA Kit |
20-abx495270 |
Abbexa |
-
EUR 9567.60
-
EUR 5095.20
-
EUR 1177.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Mouse Protein cereblon (Crbn) |
1-CSB-YP806030MO |
Cusabio |
-
EUR 604.80
-
EUR 318.00
-
EUR 2198.40
-
EUR 915.60
-
EUR 1459.20
-
EUR 400.80
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Mouse Protein cereblon(Crbn) expressed in Yeast |
Mouse Cereblon (CRBN) Protein |
20-abx652847 |
Abbexa |
-
EUR 693.60
-
EUR 309.60
-
EUR 2064.00
-
EUR 828.00
-
EUR 510.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mouse Cereblon (CRBN) Protein |
20-abx652848 |
Abbexa |
-
EUR 693.60
-
EUR 309.60
-
EUR 2064.00
-
EUR 828.00
-
EUR 510.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Human Cereblon (CRBN)ELISA Kit |
201-12-2889 |
SunredBio |
96 tests |
EUR 528 |
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
20-abx151037 |
Abbexa |
-
EUR 8853.60
-
EUR 4719.60
-
EUR 1093.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Cereblon (CRBN) ELISA Kit |
SEG676Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5677.8 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cereblon (CRBN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
SEG676Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 572.76 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cereblon (CRBN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
SEG676Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 766.8 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cereblon (CRBN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
SEG676Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3090.6 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cereblon (CRBN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Cereblon (CRBN) ELISA Kit |
4-SEG676Hu |
Cloud-Clone |
-
EUR 5738.40
-
EUR 3031.20
-
EUR 768.00
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Cereblon (CRBN) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Human Cereblon ELISA Kit (CRBN) |
RK01182 |
Abclonal |
96 Tests |
EUR 625.2 |
Cereblon (CRBN) Antibody |
20-abx171671 |
Abbexa |
|
|
|
Cereblon (CRBN) Antibody |
20-abx175781 |
Abbexa |
|
|
|
Cereblon (CRBN) Antibody |
20-abx175782 |
Abbexa |
|
|
|
Cereblon (CRBN) Antibody |
20-abx175783 |
Abbexa |
|
|
|
Cereblon (CRBN) Antibody |
20-abx111556 |
Abbexa |
|
|
|
Crbn ELISA Kit| Mouse Protein cereblon ELISA Kit |
EF014465 |
Lifescience Market |
96 Tests |
EUR 826.8 |
Human CRBN/ Protein cereblon ELISA Kit |
E0552Hu |
Sunlong |
1 Kit |
EUR 726 |
ELISA kit for Human CRBN (Cereblon) |
ELK4870 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Cereblon from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Cow Protein cereblon (CRBN) ELISA Kit |
abx516195-96tests |
Abbexa |
96 tests |
EUR 1093.2 |
|
Chicken Protein cereblon (CRBN) ELISA Kit |
abx516196-96tests |
Abbexa |
96 tests |
EUR 1093.2 |
|
Rat Protein cereblon (CRBN) ELISA Kit |
abx516199-96tests |
Abbexa |
96 tests |
EUR 886.8 |
|
Human Protein cereblon (CRBN) ELISA Kit |
abx250736-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
Human CRBN(Protein cereblon) ELISA Kit |
EH1457 |
FN Test |
96T |
EUR 681.12 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Chicken Protein cereblon, CRBN ELISA KIT |
ELI-25557c |
Lifescience Market |
96 Tests |
EUR 1113.6 |
Human Cereblon (CRBN) CLIA Kit |
20-abx495269 |
Abbexa |
-
EUR 9567.60
-
EUR 5095.20
-
EUR 1177.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Protein cereblon (CRBN) |
1-CSB-BP842761HU |
Cusabio |
-
EUR 913.20
-
EUR 367.20
-
EUR 2341.20
-
EUR 1231.20
-
EUR 1706.40
-
EUR 517.20
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Protein cereblon(CRBN) expressed in Baculovirus |
Human Protein cereblon (CRBN) |
1-CSB-CF842761HU |
Cusabio |
-
EUR 1158.00
-
EUR 798.00
-
EUR 858.00
|
|
|
Description: Recombinant Human Protein cereblon(CRBN) expressed in in vitro E.coli expression system |
Human Protein cereblon (CRBN) |
1-CSB-CF842761HUa6 |
Cusabio |
-
EUR 1158.00
-
EUR 798.00
-
EUR 858.00
|
|
|
Description: Recombinant Human Protein cereblon(CRBN) expressed in in vitro E.coli expression system |
Human Protein cereblon (CRBN) |
1-CSB-CF842761HUc7 |
Cusabio |
-
EUR 1158.00
-
EUR 798.00
-
EUR 858.00
|
|
|
Description: Recombinant Human Protein cereblon(CRBN) expressed in in vitro E.coli expression system |
Protein Cereblon (CRBN) Antibody |
20-abx003568 |
Abbexa |
-
EUR 493.20
-
EUR 710.40
-
EUR 218.40
-
EUR 376.80
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
Protein Cereblon (CRBN) Antibody |
abx200563-50ug |
Abbexa |
50 ug |
EUR 543.6 |
|
Protein Cereblon (CRBN) Antibody |
abx231954-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
Human Cereblon (CRBN) Protein |
20-abx652846 |
Abbexa |
-
EUR 693.60
-
EUR 309.60
-
EUR 2064.00
-
EUR 828.00
-
EUR 510.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Protein Cereblon (CRBN) Antibody |
20-abx322665 |
Abbexa |
|
|
|
Protein Cereblon (CRBN) Antibody |
20-abx322666 |
Abbexa |
|
|
|
Crbn ELISA Kit| Rat Protein cereblon ELISA Kit |
EF018463 |
Lifescience Market |
96 Tests |
EUR 826.8 |
CRBN ELISA Kit| Bovine Protein cereblon ELISA Kit |
EF011221 |
Lifescience Market |
96 Tests |
EUR 826.8 |
CRBN ELISA Kit| chicken Protein cereblon ELISA Kit |
EF012243 |
Lifescience Market |
96 Tests |
EUR 826.8 |
Rabbit Polyclonal antibody Anti-CRBN |
Anti-CRBN |
ImmunoStep |
50 µg |
EUR 418.8 |
Polyclonal CRBN / Cereblon Antibody (C-Terminus) |
APR11660G |
Leading Biology |
0.05mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CRBN / Cereblon (C-Terminus). This antibody is tested and proven to work in the following applications: |
CRBN ELISA Kit (Mouse) (OKCD02462) |
OKCD02462 |
Aviva Systems Biology |
96 Wells |
EUR 1028.4 |
Description: Description of target: Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2. Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the fibroblast growth factor FGF8. May play a role in memory and learning by regulating the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.057 ng/mL |
CRBN ELISA Kit (Human) (OKAN05721) |
OKAN05721 |
Aviva Systems Biology |
96 Wells |
EUR 950.4 |
Description: Description of target: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.057 ng/mL |
CRBN ELISA Kit (Human) (OKEH02269) |
OKEH02269 |
Aviva Systems Biology |
96 Wells |
EUR 794.4 |
Description: Description of target: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.2 ng/mL |
CRBN ELISA Kit (Bovine) (OKEH07882) |
OKEH07882 |
Aviva Systems Biology |
96 Wells |
EUR 1310.4 |
Description: Description of target: ;Species reactivity: Bovine;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: |
CRBN ELISA Kit (Chicken) (OKEH07883) |
OKEH07883 |
Aviva Systems Biology |
96 Wells |
EUR 1420.8 |
Description: Description of target: ;Species reactivity: Chicken;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: |
CRBN ELISA Kit (Human) (OKCD08967) |
OKCD08967 |
Aviva Systems Biology |
96 Wells |
EUR 1170 |
Description: Description of target: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutatio;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.057ng/mL |
Cereblon Binding Assay Kit |
79899 |
BPS Bioscience |
96 rxns. |
EUR 600 |
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_ The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader. |
ELISA kit for Human Protein cereblon |
EK3125 |
SAB |
96 tests |
EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Protein cereblon in samples from serum, plasma, tissue homogenates and other biological fluids. |
Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed |
ELISA-1 |
Alpha Diagnostics |
1 |
EUR 242.4 |
Mouse CRBN shRNA Plasmid |
20-abx975104 |
Abbexa |
|
|
|
CRBN Antibody |
1-CSB-PA005944GA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against CRBN. Recognizes CRBN from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
CRBN Antibody |
1-CSB-PA842761ESR1HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against CRBN. Recognizes CRBN from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
CRBN Antibody |
1-CSB-PA842761ESR2HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against CRBN. Recognizes CRBN from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
CRBN antibody |
70R-3211 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal CRBN antibody raised against the N terminal of CRBN |
CRBN antibody |
70R-16578 |
Fitzgerald |
50 ul |
EUR 522 |
Description: Rabbit polyclonal CRBN antibody |
CRBN siRNA |
20-abx901245 |
Abbexa |
|
|
|
CRBN siRNA |
20-abx912756 |
Abbexa |
|
|
|
CRBN siRNA |
20-abx912757 |
Abbexa |
|
|
|
CRBN Antibody |
8115-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: CRBN, a member of the Lon protease protein family, plays a role in brain development (1). It is a component of the DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8 (2). CRBN is thought to regulate the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1. It is widely expressed and highly expressed in brain (3,4). |
CRBN Antibody |
8115-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: CRBN, a member of the Lon protease protein family, plays a role in brain development (1). It is a component of the DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8 (2). CRBN is thought to regulate the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1. It is widely expressed and highly expressed in brain (3,4). |
CRBN Peptide |
8115P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: CRBN Peptide |
anti-CRBN |
YF-PA18916 |
Abfrontier |
50 ug |
EUR 435.6 |
Description: Mouse polyclonal to CRBN |
Cereblon Ubiquitination Homogeneous Assay Kit |
79881 |
BPS Bioscience |
384 rxns. |
EUR 820 |
Description: The Cereblon Ubiquitination Homogeneous Assay Kit is designed to measure Cereblon auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes biotin-labeled ubiquitin and proper A-screen beads to complete the pairing. This homogeneous assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. |
Crbn ORF Vector (Mouse) (pORF) |
ORF041971 |
ABM |
1.0 ug DNA |
EUR 607.2 |
Crbn ORF Vector (Mouse) (pORF) |
ORF041972 |
ABM |
1.0 ug DNA |
EUR 607.2 |
CRBN Blocking Peptide |
DF12054-BP |
Affbiotech |
1mg |
EUR 234 |
CRBN cloning plasmid |
CSB-CL842761HU1-10ug |
Cusabio |
10ug |
EUR 279.6 |
|
Description: A cloning plasmid for the CRBN gene. |
CRBN cloning plasmid |
CSB-CL842761HU2-10ug |
Cusabio |
10ug |
EUR 279.6 |
|
Description: A cloning plasmid for the CRBN gene. |
anti- CRBN antibody |
FNab01954 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against CRBN |
CRBN Polyclonal Antibody |
30601-100ul |
SAB |
100ul |
EUR 302.4 |
CRBN Polyclonal Antibody |
30601-50ul |
SAB |
50ul |
EUR 224.4 |
CRBN Blocking Peptide |
33R-2125 |
Fitzgerald |
100 ug |
EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CRBN antibody, catalog no. 70R-3211 |
CRBN Rabbit pAb |
A4722-100ul |
Abclonal |
100 ul |
EUR 369.6 |
CRBN Rabbit pAb |
A4722-200ul |
Abclonal |
200 ul |
EUR 550.8 |
CRBN Rabbit pAb |
A4722-20ul |
Abclonal |
20 ul |
EUR 219.6 |
CRBN Rabbit pAb |
A4722-50ul |
Abclonal |
50 ul |
EUR 267.6 |
Polyclonal CRBN Antibody |
APR11661G |
Leading Biology |
0.1 mg |
EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CRBN . This antibody is tested and proven to work in the following applications: |
Anti-CRBN antibody |
STJ26824 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. |
CRBN Assay Buffer |
79972 |
BPS Bioscience |
10 ml |
EUR 195 |
Description: The CRBN Assay Buffer is optimized for use with the Cereblon Binding Assay Kit (BPS Bioscience #79899). |
Cereblon intrachain TR-FRET Assay Kit |
78301 |
BPS Bioscience |
384 rxns. |
EUR 1750 |
Description: Covalent conjugation to ubiquitin (Ub) is one of the major post-translational modifications that regulates protein stability, function, and localization. Ubiquitination is the concerted action of three enzymes: a Ub-activating enzyme (E1), a Ub-conjugating enzyme (E2), and a Ub ligase (E3). The specificity and efficiency of ubiquitination are largely determined by the E3 enzyme, which directs the last step of the Ub-conjugating cascade by binding to both an E2~Ub conjugate and a substrate protein. This step ensures the transfer of Ub from E2~Ub to the substrate, leading to its mono- or poly-ubiquitination.The Cereblon (CRBN) protein via its interaction with the DNA damage-binding protein-1 (DDB1), Cullin 4 (Cul4A or Cul4B), and regulator of Cullins 1 (RoC1) forms the functional E3 Ub ligase complex. In this complex, Cereblon functions as a substrate receptor that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Cereblon complex is involved in many biological processes including cell proliferation and apoptosis. That is why it has been employed for targeted protein degradation in the treatment of cancer. Like most E3 ligases, Cereblon complex ubiquitinates itself and this auto-ubiquitination promotes its Ub ligase activity.The Cereblon intrachain TR-FRET Assay Kit is a sensitive high-throughput screening (HTS) TR-FRET Assay Kit, designed to measure Cereblon auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes a Europium cryptate-labeled Ub (donor) as well as Cy5-labeled Ub (acceptor) to complete the TR-FRET pairing. Since both the TR-FRET donor and acceptor are incorporated into poly-ubiquitin chains formed on Cereblon, this FRET-based assay requires no time-consuming washing steps, making it especially suitable for HTS applications as well as real-time kinetics analyses of polyubiquitination. |
Cereblon, FLAG-Tag Recombinant |
100255-1 |
BPS Bioscience |
10 µg |
EUR 235 |
Description: Recombinant human cereblon (CRBN), full length, encompassing amino acids 2-422(end). This construct contains an N-terminal Flag-tag. The recombinant protein was affinity purified. |
Cereblon, FLAG-Tag Recombinant |
100255-2 |
BPS Bioscience |
50 µg |
EUR 595 |
Description: Recombinant human cereblon (CRBN), full length, encompassing amino acids 2-422(end). This construct contains an N-terminal Flag-tag. The recombinant protein was affinity purified. |
Crbn sgRNA CRISPR Lentivector set (Mouse) |
K3487501 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Frit Kit |
FRIT-KIT |
Next Advance |
1each |
EUR 148.8 |
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool. |
Column Packing Kit |
PACK-KIT |
Next Advance |
1pack |
EUR 1242 |
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar. |
PCR Mycoplasma Detection Kit |
M034-Kit |
TOKU-E |
Kit |
EUR 319.2 |
CRBN Polyclonal Conjugated Antibody |
C30601 |
SAB |
100ul |
EUR 476.4 |
Human CRBN shRNA Plasmid |
20-abx959590 |
Abbexa |
|
|
|
Rat CRBN shRNA Plasmid |
20-abx988863 |
Abbexa |
|
|
|
Homo-PROTAC cereblon degrader 1 |
HY-111594 |
MedChemExpress |
10mg |
EUR 2126.4 |
Cereblon/DDB1/Cul4A/Rbx1 Complex |
100329-1 |
BPS Bioscience |
10 µg |
EUR 255 |
Description: Cereblon/DDB1/Cul4A/Rbx1 complex of human Cereblon (GenBank Accession No. NM_016302) a.a. 2-442(end) with N-terminal FLAG-tag and MW= 51 kDa, human DDB1 (GenBank Accession No. NM_001923), a.a. 1-1140(end) with N-terminal FLAG-tag and MW= 128 kDa, human Cul4A (GenBank Accession No. NM_003589), a.a. 2-759(end) with N-terminal His-tag and MW= 87 kDa, human Rbx1 (GenBank Accession No. NM_014248), a.a. 2-108(end) with N-terminal His-tag and MW= 13 kDa, co-expressed in a HEK293 expression system. |
Cereblon/DDB1/Cul4A/Rbx1 Complex |
100329-2 |
BPS Bioscience |
50 µg |
EUR 640 |
Description: Cereblon/DDB1/Cul4A/Rbx1 complex of human Cereblon (GenBank Accession No. NM_016302) a.a. 2-442(end) with N-terminal FLAG-tag and MW= 51 kDa, human DDB1 (GenBank Accession No. NM_001923), a.a. 1-1140(end) with N-terminal FLAG-tag and MW= 128 kDa, human Cul4A (GenBank Accession No. NM_003589), a.a. 2-759(end) with N-terminal His-tag and MW= 87 kDa, human Rbx1 (GenBank Accession No. NM_014248), a.a. 2-108(end) with N-terminal His-tag and MW= 13 kDa, co-expressed in a HEK293 expression system. |
Crbn sgRNA CRISPR Lentivector (Mouse) (Target 1) |
K3487502 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Crbn sgRNA CRISPR Lentivector (Mouse) (Target 2) |
K3487503 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Crbn sgRNA CRISPR Lentivector (Mouse) (Target 3) |
K3487504 |
ABM |
1.0 ug DNA |
EUR 184.8 |
CRBN Protein Vector (Mouse) (pPB-C-His) |
PV167882 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPB-N-His) |
PV167883 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPM-C-HA) |
PV167884 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPM-C-His) |
PV167885 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPB-C-His) |
PV167886 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPB-N-His) |
PV167887 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPM-C-HA) |
PV167888 |
ABM |
500 ng |
EUR 723.6 |
CRBN Protein Vector (Mouse) (pPM-C-His) |
PV167889 |
ABM |
500 ng |
EUR 723.6 |
Recombinant Mouse Protein cereblon Protein, His, Yeast-100ug |
QP9830-ye-100ug |
EnQuireBio |
100ug |
EUR 685.2 |
Recombinant Mouse Protein cereblon Protein, His, Yeast-10ug |
QP9830-ye-10ug |
EnQuireBio |
10ug |
EUR 326.4 |
Recombinant Mouse Protein cereblon Protein, His, Yeast-1mg |
QP9830-ye-1mg |
EnQuireBio |
1mg |
EUR 2763.6 |
Recombinant Mouse Protein cereblon Protein, His, Yeast-200ug |
QP9830-ye-200ug |
EnQuireBio |
200ug |
EUR 1077.6 |
Recombinant Mouse Protein cereblon Protein, His, Yeast-500ug |
QP9830-ye-500ug |
EnQuireBio |
500ug |
EUR 1806 |
Recombinant Mouse Protein cereblon Protein, His, Yeast-50ug |
QP9830-ye-50ug |
EnQuireBio |
50ug |
EUR 424.8 |
Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit |
CAS400A-KIT |
SBI |
1 kit (10 rxn) |
EUR 1332 |
|
Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit |
CAS410A-KIT |
SBI |
1 kit (10 rxn) |
EUR 798 |
Mouse CRBN(Cereblon) ELISA Kit